Alzheimer's disease and vascular factors: facts and theories
Pansari, K.; Gupta, A.; Thomas, P.
International Journal of Clinical Practice 56(3): 197-203
2002
ISSN/ISBN: 1368-5031 PMID: 12018826 Document Number: 551139
Although Alzheimer s disease is classified as a neurodegenerative dementia, in Alzheimer s dementia there is increasing evidence of an association with vascular risk factors and vascular pathology. These observations are supported by epidemiological and pathological studies. Vascular factors may play a significant role in the pathogenesis of Alzheimer s dementia. Further research is needed to explore this relationship. Modification of vascular risk factors could make a significant impact towards prevention and treatment of Alzheimer s disease, which is a distressing and prevalent condition in the community. This article considers the relationship of these vascular risk factors and potential mechanisms associated with the aetiopathogenesis of Alzheimer s dementia.