Late response to donor lymphocyte infusions in patients with chronic myeloid leukemia relapsing after allogeneic stem cell transplantation
Gómez, M.; Urbano-Ispizua, A.; Cervantes, F.; Fernández-Avilés, F.; Rovira, M.; Carreras, E.
Haematologica 87(9): 1003-1005
2002
ISSN/ISBN: 0390-6078 PMID: 12217814 Document Number: 550558
Donor lymphocyte infusions were given to 13 consecutive chronic myeloid leukemia patients in relapse after allogeneic stem cell transplantation. Of the 13 patients, 11 achieved a molecular remission and 2 a cytogenetic remission. The median time (range) in months to achieve a hematologic, cytogenetic and molecular remission was 2 (1-2), 5 (1-42) and 5 (1-30), respectively. After a median follow-up of 24 months, the median response duration is 16 months (range 1-36), and no patient shows evidence of relapse.
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