Obesity and diabetes mellitus--how are they linked?
Boden, G.
West Indian Medical Journal 51(Suppl 1): 51-54
2002
ISSN/ISBN: 0043-3144 PMID: 12050976 Document Number: 550331
There is a large body of evidence which indicates that elevated plasma levels of FFA are a major cause of insulin resistance in skeletal muscle and liver. Normalizing plasma FFA levels is, therefore, proposed as a novel approach to reduce insulin resistance, the risk of Type 2 diabetes mellitus and atherosclerotic vascular disease.