The role of copper in tumor angiogenesis--clinical implications
Nasulewicz, A.; Opolski, A.
Postepy Higieny i Medycyny Doswiadczalnej 56(6): 691-705
2002
ISSN/ISBN: 0032-5449 PMID: 12661399 Document Number: 548778
This review concerns a brief introduction into the basics of tumor blood vessels development as well as the regulatory mechanisms of this process. The role of copper ions in tumor angiogenesis is discussed. The new antiangiogenic therapies based on a reduction of copper level in tumor microenvironment are reviewed.
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