Characterization of antilysozyme and anticomplement signs in brucellae during experimental infection
Sheenkov, N.V.; Iakovlev, A.G.; Skachkov, M.V.; Iartseva, N.N.; Cherkasov, S.V.; Sharapova, E.A.; Bukharin, O.V.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 2002(3): 12-16
2002
ISSN/ISBN: 0372-9311 PMID: 12141029 Document Number: 548616
The dependence of the course of experimental infection on the initial level of antilysozyme activity of Brucella clones was studied using 40 noninbred guinea pigs. As revealed in this study, the antilysozyme sign of brucellae influenced the pathogenesis of brucellosis, facilitating the prolonged survival of brucellae in the host body. The results thus obtained may be used for the prognostication of the course of Brucella infection.