Bacteria isolated from surgical infections and their susceptibilities to antimicrobial agents--special references to bacteria isolated between April 2000 and March 2001
Shinagawa, N.; Manabe, T.; Takeyama, H.; Hasegawa, M.; Hirata, K.; Mukaiya, M.; Katsuramaki, T.; Taniguchi, M.; Ushijima, Y.; Mashita, K.; Aikawa, N.; Sekine, K.; Ishikawa, S.; Mizuno, A.; Iwai, S.; Kato, K.; Kinoshita, H.; Morimoto, K.; Sato, T.; Fujimoto, M.; Yura, J.; Tanimura, H.; Ohnishi, H.; Maeda, T.; Sueda, T.; Takesue, Y.; Tanaka, N.; Iwagaki, H.; Yokoyama, T.; Hiyama, E.; Fuchimoto, S.; Inoue, F.; Kimura, H.; Ikeda, S.; Yasunami, Y.; Konaga, E.; Takeuchi, H.; Suzuki, Y.; Nakane, Y.
Japanese Journal of Antibiotics 55(6): 730-763
2002
ISSN/ISBN: 0368-2781 PMID: 12621729 Document Number: 547277
Tendency of isolated bacteria from infections in general surgery and their antimicrobial susceptibilities during the period from April 2000 to March 2001 were investigated in a multicenter study in Japan, and the following results were obtained. The number of cases investigated as objectives was 234 for one year. A total of 388 strains (136 strains from primary infections and 252 strains from postoperative infections) were isolated from 165 cases (70.5% of total cases). In primary infections, anaerobic Gram-positive bacteria were predominant, while from postoperative infections, aerobic Gram-positive bacteria were predominant. Among aerobic Gram-positive bacteria, the isolation rate of Enterococcus faecalis was the highest, followed by that of Staphylococcus aureus from postoperative infections. Among anaerobic Gram-positive bacteria, the isolation rate of Peptostreptococcus spp. was the highest from both types of infections. Among aerobic Gram-negative bacteria, Escherichia coli was the most predominantly isolated from primary infections, followed by Klebsiella pneumoniae and Pseudomonas aeruginosa in this order, and from postoperative infections, P. aeruginosa was the most predominantly isolated, followed by Enterobacter spp. and Klebsiella spp. Among anaerobic Gram-negative bacteria, the isolation rate of Bacteroides fragilis group was the highest from both types of infections. There was no vancomycin-resistant S. aureus nor Enterococcus spp. Among anaerobic bacteria, there were many resistant strains against penicillins and cephems with MICs higher than 100 micrograms/ml, and the same trend was observed among other Bacteroides spp. and Prevotella spp.