Common variable immunodeficiency and eosinophilic fasciitis
Di Gioacchino, M.; Masci, S.; Paolini, F.; Verna, N.; Angelucci, D.; Cavallucci, E.; Paganelli, R.
European Journal of Dermatology Ejd 12(1): 73-74
2002
ISSN/ISBN: 1167-1122 PMID: 11809601 Document Number: 545432
The association of eosinophilic fasciitis and immunological defects is rare, especially hypogammaglobulinemia. We report a case of eosinophilic fasciitis occurring in a female, 53 years old, with common variable immunodeficiency. The diagnosis of common variable immunodeficiency was established by chance observation of persistently low levels of all immunoglobulin classes unrelated to protein loss or immunosuppressive treatment, one year after the appearance of eosinophilic fasciitis, which is usually characterized by hypergammaglobulinemia. Our description may prompt the investigation of an increased rate of simultaneous occurrence of eosinophilic fasciitis and common variable immunodeficiency.
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