The effect of HJ-1 NO--HFJV respirator on treating pulmonary edema caused by seawater drowning
Fan, Y.; Dong, W.; He, J.; Du, L.; Xu, G.; Liu, X.; Pei, Y.; Fu, G.; Ma, G.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 19(3): 526-528
2002
ISSN/ISBN: 1001-5515 PMID: 12557539 Document Number: 544029
The study was to observe the therapeutic effect of HJ-1 NO--HFJV respirator on treating pulmonary edema caused by seawater drowning. Seawater was infused into the rabbit's lung to establish the animal model of pulmonary edema caused by seawater drowning(PE-SWD). Then the animals were divided into three groups: simple PE-SWD model as control group, treat group(animal model treated with HFJV respirator and four medicines) and HFJV respiratior plus NO group. Pao2, Sao2 and pH were measured by the blood-gas analyzer. The survival time and seawater drowing-respiratiory distress syndrom(SW-RDS) were observed. The results showed that Pao2, Sao2 in NO group were remarkably higher than that of PE-SWD control group, and the survival time was longer than that of medicine treated group and the incidence of SW-RDS decreased to zero. We assume that HJ-1 NO-HFJV respirator is efficient on treating pulmonary edema.