Effects of different types of stress on the accumulation of calcium in the liver, and its functional activity
Miroshnichenko, A.O.; Liashenko, V.P.; Lukashov, S.M.
Fiziolohichnyi Zhurnal 48(5): 22-27
2002
ISSN/ISBN: 2522-9028 PMID: 12449610 Document Number: 543252
The dynamics of calcium content in the liver under alimentary and immobilizing stresses was studied. To evaluate the functional state of the liver we conducted a simultaneous recording of the cholesterin level in the serum. Calcium has been shown to be accumulated in that organ, and it correlated positively with the level of cholesteremia. At a prolonged action of the stressors calcium accumulation was more significant in animals under immobilizing stress, as compared with those under alimentary one. The dynamic saturation of the liver with calcium was shown to reflect the stages of the stress. We suggest that calcium serves the trigger for the synthesis of cholesterin in the cells of the liver at stress. Thus, an adaptive reaction of the liver, and a possible mechanism of the hypercholesteremia initiation under stresses of different genesis have been demonstrated.