Top Abstract Purchase Related
Home
>
Node
>
Subnode

The expression of CD44v6 in oral cancer with different biological behavior

Tian, Z.; Guo, W.; Zhang, W.-g.

Shanghai Kou Qiang Yi Xue 11(4): 353-355

2002

ISSN/ISBN: 1006-7248
PMID: 14983379
Document Number: 543109
To investigate a potential mechanism of invasion and metastasis of oral cancers,and the possibility of the adhesion molecules being markers for evaluating the prognosis of oral cancers. Randomly selecting achieved paraffin blocks, including 60 cases of squamous cell carcinoma(SCC), 30 cases of verrucous carcinoma(VC) of oral mucosa and 30 cases of basal cell carcinoma(BCC) of epidermis. Using immunohistochemistry method (Envision) to detect the expression of CD44v6 antibody and observe under light microscope. The expression level of CD44v6 protein in SCC had no significant difference between SCC and VC, but significant differences of CD44v6 expression were showed between BCC and SCC(P<0.01), as well BCC and VC(P<0.01). CD44v6 takes part in the homogeneous adhesion of normal oral mucosa and epidermis and may play a role in maintaining the characteristics of epithelial differentiation, but it has shown no correlation with the biological behavior of oral cancers.

Document emailed within 1 workday
Secure & encrypted payments

Hou, Y-feng.; Yuan, S-tao.; Li, H-cheng.; Wu, J.; Lu, J-song.; Lu, L-juan.; Liu, G.; Shen, Z-zhou.; Ding, J.; Shao, Z-min. 2005: In vitro study of the effects of estrogen receptor beta expression on the biological behavior of a human breast cancer cell line Zhonghua Zhong Liu Za Zhi 27(7): 389-392
Jin, Z.-Q.; Yuan, R.-T.; Jia, M.-Y. 2008: Clinical biological behavior and treatment strategy of hemangioma in oral and maxillofacial region Shanghai Kou Qiang Yi Xue 17(5): 449-452
Tian, H-mei.; Fu, J.; Cao, D-yan.; Shi, X-Yan.; Li, J-xiu.; Shao, C-jun.; Ma, D-mei.; Huang, H.; Li, M.; Qu, P.; Liu, Z-yang.; Zhang, W. 2003: Heterogeneity of human breast cancer cells and their biological behavior Zhonghua Zhong Liu Za Zhi 25(6): 535-537
Mogi, S.; Dang, D.; Van Waes, C.; Ellis, D.; Atakilit, A.; Ramos, D.M. 2005: The expression of integrin alpha(v)beta6 promotes the epithelial cell morphology and suppresses invasive behavior in transformed oral keratinocytes Anticancer Research 25(2a): 751-755
Guadagni, F.; Roselli, M.; Cosimelli, M.; Ferroni, P.; Spila, A.; Cavaliere, F.; Arcuri, R.; Carlini, S.; Mariotti, S.; Gandolfo, G.M.; Casciani, C.U.; Greiner, J.W.; Schlom, J. 1996: TAG-72 expression and its role in the biological evaluation of human colorectal cancer Anticancer Research 16(4b): 2141-2148
Liu, Y.; Zhang, X.; Yu, F.; Liu, J.; Zhang, M.; Zhang, S.; Hao, X.; Zhang, J. 2014: Prognostic significance of Ki-67 expression before and after neoadjuvant chemotherapy in different biological breast cancer phenotypes Zhonghua Zhong Liu Za Zhi 36(9): 671-676
Hu, L.-h.; Wu, Y.; Lu, G.-h.; Chen, Q.-y.; Wang, Y.-h.; Zhou, J.-y. 2010: Correlation of the expression of IIi β-tubulin and MDR1 protein with biological features of non-small cell lung cancer Zhonghua Zhong Liu Za Zhi 32(10): 762-766
Famulski, W.; Sulkowska, M.; Miller-Famulska, D.; Terlikowski, S.; Guzińska-Ustymowicz, K.; Sulkowski, S. 2002: P53 protein expression in oral squamous cell cancer in relation to some of its clinicopathological variables Folia Histochemica et Cytobiologica 40(2): 203-204
Vairaktaris, E.; Yapijakis, C.; Nkenke, E.; Serefoglou, Z.C.; Chatzitheofylaktou, A.; Vassiliou, S.; Derka, S.; Vylliotis, A.; Perrea, D.; Neukam, F.W.; Patsouris, E. 2007: A metalloproteinase-13 polymorphism affecting its gene expression is associated with advanced stages of oral cancer Anticancer Research 27(6b): 4027-4030
Vairaktaris, E.; Serefoglou, Z.; Yapijakis, C.; Vylliotis, A.; Nkenke, E.; Derka, S.; Vassiliou, S.; Avgoustidis, D.; Neukam, F.W.; Patsouris, E. 2007: High gene expression of matrix metalloproteinase-7 is associated with early stages of oral cancer Anticancer Research 27(4b): 2493-2498
Hellberg, D.; Stendahl, U. 2005: The biological role of smoking, oral contraceptive use and endogenous sexual steroid hormones in invasive squamous epithelial cervical cancer Anticancer Research 25(4): 3041-3046
Lo Muzio, L.; Santarelli, A.; Panzarella, V.; Campisi, G.; Carella, M.; Ciavarella, D.; Di Cosola, M.; Giannone, N.; Bascones, A. 2007: Oral squamous cell carcinoma and biological markers: an update on the molecules mainly involved in oral carcinogenesis Minerva Stomatologica 56(6): 341-347
Kawasaki, G.; Yoshitomi, I.; Yanamoto, S.; Yamada, S.-I.; Kawano, T.; Mizuno, A. 2010: Immunohistochemical and clinicopathological study of thymidylate synthase, dihydropyrimidine dehydrogenase, and orotate phosphoribosyl transferase expression in oral cancer patients responding to UFT Gan to Kagaku Ryoho. Cancer and ChemoTherapy 37(6): 1035-1039
Maeda, G.; Chiba, T.; Okazaki, M.; Satoh, T.; Taya, Y.; Aoba, T.; Kato, K.; Kawashiri, S.; Imai, K. 2005: Expression of SIP1 in oral squamous cell carcinomas: implications for E-cadherin expression and tumor progression International Journal of Oncology 27(6): 1535-1541
Ries, J.C.; Schreiner, D.; Steininger, H.; Girod, S.C. 1998: p53 mutation and detection of p53 protein expression in oral leukoplakia and oral squamous cell carcinoma Anticancer Research 18(3b): 2031-2036
Brändstedt, J.; Wangefjord, S.; Nodin, Börn.; Eberhard, J.; Jirström, K.; Manjer, J. 2014: Associations of hormone replacement therapy and oral contraceptives with risk of colorectal cancer defined by clinicopathological factors, beta-catenin alterations, expression of cyclin D1, p53, and microsatellite-instability Bmc Cancer 14: 371
Zhang, J.; Zeng, Y.; Zheng, J.; Xu, J. 2013: Expression of Prion protein and its clinical significance in oral squamous cells carcinoma and oral leukoplakia Zhonghua Kou Qiang Yi Xue Za Zhi 48(12): 752-754
Salo, T. 2001: Factors that increase the risk of oral cancer and cancer-resembling changes of oral mucosa Duodecim; Laaketieteellinen Aikakauskirja 117(9): 966-977
Zhu, R.; Jian, X.-C.; Liu, D.-Y.; Zhou, C.; Wang, Y. 2017: Expression of PTPRZ1 in oral squamous cell carcinoma originated from oral submucous fibrosis and its clinical significance Shanghai Kou Qiang Yi Xue 26(2): 198-203
Razenberg, T.P. 1988: Biological markers of suicidal behavior Nederlands Tijdschrift Voor Geneeskunde 132(40): 1861