Efficacy and tolerance assessment of mitrazapine in the treatment of depression in the elderly--preliminary report
Florkowski, A.; Gruszczyński, W.; Zboralski, K.
Psychiatria polska 36(6 Suppl): 143-146
2002
ISSN/ISBN: 0033-2674 PMID: 12647433 Document Number: 543043
Depressive disorders are often met in the elderly, its course is usually protracted and outcome sometimes fatal. The purpose of this study is evaluation of efficacy and tolerance of mirtazapine in this group of patients. 24 patients (mean age 73.8) with major depressive episode (> 20 in 17-tem HAMD; also CGI scale was used for evaluation) without psychotic features were treated with mirtazapine (30-45 mg) for 6 months. Improvement (especially such symptoms as better mood and sleep, less anxiety) could be seen in 75% of patients.