The role of dendritic cells in neurodegenerative diseases

Iribarren, P.; Cui, Y.-H.; Le, Y.; Wang, J.M.

Archivum Immunologiae et Therapiae Experimentalis 50(3): 187-196

2002


ISSN/ISBN: 0004-069X
PMID: 12098934
Document Number: 542464
Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs) involved in the induction of adaptive immune responses. The presence of DCs in the central nervous system (CNS) and the active participation of the immune system in a variety of neurodegenerative diseases have been demonstrated. This review will discuss recent findings pertinent to DCs and other antigen-presenting cells in the CNS in health and disease states.

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