Tumor markers in malignant lymphoma
Banno, S.; Ueda, R.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 29(1): 149-153
2002
ISSN/ISBN: 0385-0684 PMID: 11816473 Document Number: 541155
The clinical usefulness of tumor markers for malignant lymphoma is thought to be in monitoring the therapeutic effect and as a prognostic factor before treatment. The former include specific biological marker such as soluble interleukin-2 receptor measured by ELISA. The latter are cellular prognostic markers detected by immunohistological and flow cytometric analysis. The cyclin D1 over-expression of mantle cell lymphoma in diffuse large B-cell lymphoma, which should be recommended for myeloablative therapy, is a significantly poor prognostic risk factor.
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