Acute tubular necrosis with acute renal failure during the first month of treatment with 5-amino-salicylate (Pentasa(R))

Beaulieu, S.; Rocher, P.; Hillion, D.; Nochy, D.; Tennenbaum, R.; Vitte, R.é-L.; Eugène, C.; Beaulieu, S; Rocher, P; Hillion, D; Nochy, D; Tennenbaum, R; Vitte, R.é-L; Eugène, C

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Acute tubular necrosis with acute renal failure during the first month of treatment with 5-amino-salicylate (Pentasa (R) )

Beaulieu, S.; Rocher, P.; Hillion, D.; Nochy, D.; Tennenbaum, R.; Vitte, R.é-L.; Eugène, C.

Gastroenterologie Clinique et Biologique 26(4): 412-414

2002

ISSN/ISBN: 0399-8320

PMID: 12070416

Document Number: 540899

We report a case of acute tubular necrosis in a patient with Crohn's disease treated by 5-amino-salicylate (Pentasa(R)) since one month. Normalization of renal biological parameters occurred rapidly after treatment withdrawal. This case raises the question of the optimal modalities of monitoring of renal function during treatment with 5-amino-salicylate.