Effects of two preanesthetic regimens for ophthalmic surgery on intraocular pressure and cardiovascular measurements in dogs
Tamura, E.Yuriko.; Barros, P.Sergio.de.Moraes.; Cortopassi, S.Renata.Gaido.; Ambrósio, A.Magalhães.; Fantoni, D.Tabacchi.
Veterinary Therapeutics Research in Applied Veterinary Medicine 3(1): 81-87
2002
ISSN/ISBN: 1528-3593 PMID: 12050831 Document Number: 540867
The effects of different preanaesthetic medications (acepromazine plus either meperidine or butorphanol) given before the induction of anaesthesia with midazolam and ketamine on intraocular pressure, heart rate, and arterial blood pressure were investigated in 20 dogs. Following administration of preanaesthetic and induction of anaesthesia, dogs were intubated and anaesthesia was maintained with halothane for 10 min. Intraocular pressure was significantly higher (P<0.05) at several evaluations for dogs premedicated with acepromazine/meperidine than for those premedicated with acepromazine/butorphanol. Mean heart rate and diastolic arterial blood pressure were significantly (P<0.05) higher 5 min after administration of acepromazine/meperidine than after acepromazine/butorphanol. Results of this study suggest that acepromazine/butorphanol is a satisfactory preanaesthetic combination to use before induction of anaesthesia with midazolam and ketamine for ophthalmic surgery in dogs.