Recent advance in adjuvant therapy for breast cancer
Shimizu, C.; Watanabe, T.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 29(13): 2458-2469
2002
ISSN/ISBN: 0385-0684 PMID: 12506467 Document Number: 540626
Adjuvant systemic therapy has contributed to a significant improvement of disease-free and overall survival in addition to surgery and irradiation to the local disease. The adjuvant therapy to a patient is determined integrating the information on estimated risk of recurrence, benefit and harm of the therapy and the patient's value. In this review, the state of the art of adjuvant therapy is discussed from several aspects, such as interpretation and evaluation of risk, the best available evidences on adjuvant systemic therapy, the future direction of primary therapy for breast cancer, and patient-oriented decision making.