Subjective wellbeing and somatic markers in methadone substitution. Evaluation of 61 heroin addicts
Giacomuzzi, S.M.; Riemer, Y.; Kemmler, G.; Ertl, M.; Richter, R.; Rössler, H.; Hinterhuber, H.
Fortschritte der Medizin. Originalien 119(3-4): 103-108
2001
ISSN/ISBN: 1438-3276 PMID: 11789120 Document Number: 539930
In 61 patients with the ICD-10 diagnosis "heroin dependence" an evaluation of subjective well-being with consideration given to coexisting symptoms prior to and 4 months after initiation of methadone maintenance. The Lancashire Quality of Life Profile and, for the clinical physical side effects, the opioid withdrawal scale proposed by Bradley and Seldenburg, were used. Additionally, urinalysis was performed. Statistically appreciable differences were found between the two groups in terms of drug-specific side effects, somatic satisfaction scales, and consumption of medications and co-use of addictive drugs. Further statistically evident inter-group differences were seen with regard to mental well-being. Overall, methadone maintenance leads to a rapid improvement in subjective well-being and to a relevant reduction in concurrent physical symptoms.