Ultrastructural and Ca/P changes of the regenerated bone after mandibular distraction in goats
Hu, J.; Li, J.; Wang, D.; Liao, Y.
Hua Xi Kou Qiang Yi Xue Za Zhi 19(1): 9
2001
ISSN/ISBN: 1000-1182 PMID: 12539625 Document Number: 539200
The aim of this study was to examine the ultra structural and the changes of Ca/P elements of the new bone resulting from mandibular distraction osteogenesis. Bilateral mandibular osteotomies were performed in six goats. The mandibles in all animals were lengthened 10 mm using a custom made distracter. Each 2 goats were sacrificed respectively at 2, 4 and 8 weeks after completion of distraction. The distracted callus were harvested and processed for SEM evaluation and Ca/P ratio analysis. The newly generated bone in distraction gap was confirmed by SEM examination, and the contents of Ca, P were found to be elevated with the maturity of distracted callus. This study suggested that newly formed bone by mandibular distraction osteogenesis in goats could be remodeled to normal bone.