Inhibitors of neoangiogenesis in antineoplastic therapy
Opolski, A.; Wietrzyk, J.
Postepy Higieny i Medycyny Doswiadczalnej 55(3): 369-385
2001
ISSN/ISBN: 0032-5449 PMID: 11505638 Document Number: 539105
The role of angiogenesis in tumor growth and metastasis is discussed. The endogenous activators and inhibitors of tumor angiogenesis are presented and their mechanisms of action are reviewed. An overview on angiogenesis as a new potential target of antitumor therapy is described. The clinical trials of various antiangiogenic agents are briefly summarized and their differential mechanisms of action are discussed.