Clinical significance of microbiological monitoring of infective agents in an urological hospital in the selection of antibacterial therapy regimens
Derevianko, I.I.; Nefedova, L.A.; Lavrinova, L.N.; Prudnikova, S.A.
Urologiia 2001(4): 11-15
2001
ISSN/ISBN: 1728-2985 PMID: 11569227 Document Number: 537357
Individual microbiological examination of each patient can improve significantly the response of urological patients to antibacterial therapy. 6000 cultures of opportunistic microorganisms isolated from patients with various infectious-inflammatory diseases were studied. Most of them were gram-negative: P. aeruginosa, E. coli, Enterobacter spp., Proteus spp. Of gram-positive most frequently occurred Staphylococcus spp and Enterococcus faecalis. The cultures showed different spectrum of the sensitivity to antibacterial drugs used in urological practice. The choice of etiotropic therapy was the easiest in E. coli infection, the hardest in P. aeruginosa and Enterobacter pylori infection. Combined treatment of complicated urological infections with gentamycin, ampicillin, carbnicilline, azlocillin is much more effective than monotherapy. P. aeruginosa is more sensitive to cephalosporins, fluoroquinolins, carbapenems and combination of aminoglycosides with betalactame drugs.