Long-term follow up of angioplasty for cerebral vasospasm
Srinivasan, J.; Moore, A.; Eskridge, J.; Winn, H.R.; Newell, D.W.
Acta Neurochirurgica. Supplement 77: 195-197
2001
ISSN/ISBN: 0065-1419 PMID: 11563285 Document Number: 537291
Cerebral angioplasty has been reported to be useful for the treatment of symptomatic cerebral vasospasm following subarachnoid hemorrhage [3]. Recent data indicates that angioplasty may be effective in preventing the development of vasospasm [7]. However, the long-term effects of cerebral angioplasty on the human cerebral circulation are not known. In the coronary circulation, complications of angioplasty for atherosclerotic disease include restenosis in 30% of vessels, occlusion of the vessel, transient loss of vascular reactivity, and long-term endothelial dysfunction [4]. In atherosclerotic vessels, angioplasty induces vascular injury and initiates intimai hyperplasia, deposition of extracellular matrix, and ultimately results in vessel remodeling.