The routine coagulation tests along with activated protein C resistance (APC-R) in population of women applying for oral contraceptives
Kostecka, I.; Dabrowska, M.; Osada, J.; Suchowierska, M.; Wołczyński, S.
Przeglad Lekarski 58(12): 1038-1040
2001
ISSN/ISBN: 0033-2240 PMID: 12041017 Document Number: 536293
The routine coagulation tests along with activated protein C resistance (APC-R) were studied in North-Eastern Poland women, applying for oral contraceptives. The APTT, PT and fibrinogen concentration were evaluated in 128 women, aged 20-40 years, by means of nephelometric method. For estimation of APC-R, Coatest APC Resistance V test was used. The abnormalities in routine coagulation test were found in 13.3% of studied women. The resistance to activated protein C was observed among 4.3% of women with normal results of routine coagulation tests. The thrombotic event occurred in one of five APC-R positive woman. There was no correlation between APC-V ratio and APTT, PT or fibrinogen values.