Desmoplastic astrocytoma of infancy--a case report
Kandalkar, B.; Shah, V.; Shet, T.
Indian Journal of Pathology and Microbiology 44(3): 329-332
2001
ISSN/ISBN: 0377-4929 PMID: 12024924 Document Number: 534868
Desmoplastic cerebral astrocytoma of infancy (DCAI) is a rare tumor which shows spindle cells embedded in an extremely desmoplastic stroma. We describe a case of DCAI seen in the frontoparietal region of brain in a three-month-old infant. Microscopically classic histology of DCAI was seen. On immunohistochemistty the tumor showed strong Vimentin, S-100 and Glial Fibrillary Acidic Protein (GFAP) positivity. The brain adjacent to the tumor-showed multi-cystic transformation and the tumor formed a solid area in the wall of this cystic structure. This adjacent brain showed mild disarray of architecture and gliosis. Three months after surgery this infant was alive and well.