Implementing the Jadelle implant for women living with HIV in a resource-limited setting: concerns for drug interactions leading to unintended pregnancies

Perry, S.H.; Swamy, P.; Preidis, G.A.; Mwanyumba, A.; Motsa, N.; Sarero, H.N.

Aids 28(5): 791-793

2014


ISSN/ISBN: 1473-5571
PMID: 24401645
DOI: 10.1097/qad.0000000000000177
Document Number: 534255
An analysis of 570 HIV-infected women in Swaziland using the Jadelle implant showed that age, condom use, the provider who placed the implant, and CD4 cell count had no effect on unintentional pregnancy rates. Antiretroviral regimen at the time of pregnancy, however, correlated with pregnancy outcomes (P < 0.001). None of the women on nevirapine or lopinavir/ritonavir-based regimens (n = 208 and 13, respectively) became pregnant, whereas 15 women on efavirenz (n = 121; 12.4%) became pregnant.

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