Immunological marker activity in first episode schizophrenic patients
Szulc, A.; Galińska, B.; Konarzewska, B.; Gudel-Trochimowicz, I.; Popławska, R.
Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego 10(60): 450-452
2001
ISSN/ISBN: 1426-9686 PMID: 11503261 Document Number: 532810
We evaluated immune-inflammatory markers in 32 first-episode schizophrenic patients during exacerbation of symptoms and during clinical improvement. Mean concentrations of sIL-2R and IFN-g was higher and mean concentration of sIL-6R was lower in cell cultures from blood of schizophrenic patients than in normal controls and there was no difference in IL-2 concentration. There was no correlation between concentrations of cytokines and demographic and clinical data. Our results may suggest that immune system disturbances could be observed in schizophrenia at the onset of the disease.