Effect of products of alphaS1-casein proteolysis on the activity of angiotensin-converting enzyme

Iukalo, V.H.

Ukrains'kyi Biokhimichnyi Zhurnal 73(5): 28-32

2001


ISSN/ISBN: 0372-3909
PMID: 12035500
Document Number: 531289
The influence of alpha s1-casein proteolysis products of cow milk on the activity of angiotensin-converting enzyme (ACE) has been investigated. The peptide fraction has been obtained after incubation of alpha s1-casein with different strains Lactococcus lactis ssp. lactis and pepsin. The peptides with low molecular weight has been obtained with the help of a gel filtration. It is shown, that such peptides received with the help of some strains of Lactococcus lactis ssp. lactis and pepsin are capable to inhibit the activity of ACE. A conclusion about possibility of appearing antihypertensive peptides as a result of proteolitic processes in milk products has been made.

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