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Castleman's disease and superior vena cava thrombi: a rare presentation and a review of the literature

Dhingra, H.; Sondhi, D.; Fleischman, J.; Ayinla, R.; Chawla, K.; Rosner, F.

Mount Sinai Journal of Medicine new York 68(6): 410-416

2001

ISSN/ISBN: 0027-2507
PMID: 11687872
Document Number: 529581
Castleman's disease is a clinicopathological entity in which growth of lymphoid tissue is unregulated. It may present as asymptomatic involvement of one lymph node group or as a multicentric disease with systemic symptoms. Unlike localized disease, for which surgical excision is curative regardless of the histological type, multicentric disease often necessitates aggressive systemic therapy and portends a poor outcome. Superior vena caval thrombosis is an uncommon manifestation associated with Castleman's disease.

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