An unusual presentation of opioid-like syndrome in pediatric valproic acid poisoning
Espinoza, O.; Maradei, I.; Ramírez, M.; Pascuzzo-Lima, C.
Veterinary and Human Toxicology 43(3): 178-179
2001
ISSN/ISBN: 0145-6296 PMID: 11383666 Document Number: 529383
We report a 3-y-o boy who accidentally poisoned himself with valproic acid (VPA). Clinical features included profound coma, depressed respiration and miosis. Treatment included naloxone, gastric lavage, and activated charcoal and a saline cathartic. The patient fully recovered and was discharged 24 h after the admission. Prompt use of naloxone is advised whenever the triad of coma, pinpoint pupils and depressed respiration concur with the clinical possibility of VPA intoxication.