Evaluation of venotropic drugs by venous gas plethysmography. a study of procyanidolic oligomers

Royer, R.J.; Schmidt, C.L.

La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 57(47-48): 2009-2013

1981


ISSN/ISBN: 0037-1777
PMID: 6276983
Document Number: 5293
Venous tone in the lower limbs can be measured by venous occlusion gas plethysmography before and after giving venotropic drugs. Four groups, each of which included ten patients with widespread varicose veins, were given different medications. Each patient was studied by plethysmography during the first five hours following drug ingestion. In untreated controls, venous tone decreased during rest. A reference drug was uneffective. Increase in venous tone induced by 150 mg of procyanidolic oligomers was comparable to that which followed ingestion of a high dose of hamamelis-hydrastis mixture.

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Evaluation of venotropic drugs by venous gas plethysmography. a study of procyanidolic oligomers