Evaluation of bone metastases from renal cell carcinoma
Tsuda, S.; Koga, S.; Nishikido, M.; Tsurusaki, T.; Igawa, T.; Noguchi, M.; Kanda, S.; Matsuya, F.; Kanetake, H.
Hinyokika Kiyo. Acta Urologica Japonica 47(3): 155-158
2001
ISSN/ISBN: 0018-1994 PMID: 11329954 Document Number: 528228
Forty-two cases of bone metastasis from renal cell carcinoma were examined. Thirty of the cases had bone metastases at the time of renal cell carcinoma. Bone metastasis appeared after treatment of the primary site in 12 cases. Fifteen cases had only bone metastasis and another 27 had metastasis in multiple organs. The total cause-specific survival curve of these patients was 10% at 5 years. All patients with bone metastases died of cancer within 5 years after the bone metastases had developed. There was no significant difference in the survival rate between patients with bone metastases and patients with lung metastases. We investigated the prognostic value of laboratory studies in bone metastases of renal cell carcinoma. However, no significant markers were detected for bone metastases. The 6 patients were treated with decompressed laminectomy (2), wide resection (3) and excision of the metastatic lesions (3). The quality of life was improved in all the patients although they died of cancer.