Familial autoimmune myasthenia gravis
Tan, J.H.; Ho, K.H.
Singapore Medical Journal 42(4): 178-179
2001
ISSN/ISBN: 0037-5675 PMID: 11465320 Document Number: 527849
Familial Autoimmune Myasthenia Gravis (FAMG) is rarely reported. We present a mother and son with late-onset mild to moderate ocular disease, low acetylcholine receptor antibody titre and the absence of a thymoma. Both responded well to low doses of anticholinesterase. HLA typing revealed that they did not share the usual HLA antigens or haplotypes with that previously reported in Caucasian and Chinese sporadic Myasthenia Gravis. Chinese FAMG may be associated with HLA antigens different from that of sporadic MG.