IS-741 (Ishihara Sangyo)
Bassi, C.
Current Opinion in Investigational Drugs 2(4): 510-512
2001
ISSN/ISBN: 1472-4472 PMID: 11566008 Document Number: 526577
IS-741 is a phospholipase A2 (PLA2) inhibitor under development by Ishihara Sangyo Kaisha and Sumitomo as a potential treatment for pancreatitis 1187575]. Sumitomo is developing the drug in phase II trials for acute pancreatitis 13990261. In an animal model, IS-741 has been shown to prevent pancreatitis-associated lung injury following endotoxemia [337503].