Surgical management of irradiation failures in T1-T2 squamous cell carcinoma of the glottic larynx
Virtaniemi, J.A.; Hirvikoski, P.P.; Kumpulainen, E.J.; Johansson, R.T.; Kosma, V.M.
Anticancer Research 21(6a): 4185-4188
2001
ISSN/ISBN: 0250-7005 PMID: 11911316 Document Number: 526492
The purpose of this study was to analyse the results of salvage surgery after failure of irradiation to control the primary T1-T2 glottic cancer. Ninety-eight patients with T1 and T2 squamous cell cancer of the glottic larynx were treated with curative intent by radiotherapy. The tumour recurred in 22 of the 98 (22%) patients. Surgical management consisted of total and frontolateral laryngectomy. Survival rates were calculated from the date of the salvage operation. Two of the 22 patients refused to undergo salvage surgery and one patient had pulmonary metastasis. Of the 19 patients who underwent salvage surgery, 14 (74%) had total laryngectomy and 5 (26%) had frontolateral laryngectomy. The operations were curative in 15 (79%) of the 19 patients. The overall 5-year survival rate after surgery was 78%. Stringent follow-up of patients with irradiated T1 and T2 glottic laryngeal cancer is essential to permit a successful salvage.