Chronic hepatitis C in HIV-infected patients. Unfavorable interaction of HIV and HCV infection
Mauss, S.
MMW Fortschritte der Medizin 142(Suppl 1): 60-62
2000
ISSN/ISBN: 1438-3276 PMID: 10863316 Document Number: 525973
HIV coinfection promotes the progression of chronic hepatitis C. The increased hepatic mortality and improved life expectancy of HIV-positive patients warrants treatment of chronic hepatitis C in those infected with HIV. The treatment of hepatitis C considered standard for HIV-negative and, in principle, also for HIV-positive patients is the combination of interferon alpha with ribavirin. Possible interaction with the antiretroviral treatment by ribavirin must, however, taken into account. Although new therapeutic approaches are available, they have not yet been adequately validated terms of their efficacy and safety.