Aspects of the transport and delivery of antisense oligonucleotides
Juliano, R.L.; Yoo, H.
Current Opinion in Molecular Therapeutics 2(3): 297-303
2000
ISSN/ISBN: 1464-8431 PMID: 11249624 Document Number: 525890
This article will examine recent developments concerning the cellular uptake and subcellular trafficking of antisense oligonucleotides. It will also examine the merits of various delivery strategies for oligonucleotides. The use of conjugates of oligonucleotides with 'cell penetrating peptides' as a promising delivery technology will be emphasized.
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