Identification of the human Y-chromosomal microsatellite locus DYS19 from degraded DNA
Szibor, R.; Kayser, M.; Roewer, L.
American Journal of Forensic Medicine and Pathology 21(3): 252-254
2000
ISSN/ISBN: 0195-7910 PMID: 10990287 Document Number: 524949
STR DYS19 seems to be one of the most useful markers for population genetic, evolutionary, and forensic applications. However, the authors have noticed that the amplification of the DYS19 polymorphism fails when highly degraded DNA is used as a template. The authors designed a new pair of primers that reduce the DYS19 fragment sizes compared with those of the known protocol. Using these primers, an improved success rate can be achieved, particularly when putrefied samples are under investigation.