Morphological changes in dental enamel after fluoride gel application in vitro
Kukleva, M.P.
Folia Medica 42(2): 71-74
2000
ISSN/ISBN: 0204-8043 PMID: 11217290 Document Number: 524108
The investigations of in vitro models precede the clinical studies. Using these studied we can investigate the effect upon the enamel of different agents for local application. The purpose of this study was to investigate the ultrastructural changes in a normal and partially demineralized enamel after 0.42% fluoride gel application in vitro using scanning electron microscopy. The experiment was performed on 20 premolars extracted for orthodontic indications. Symmetrical specimens were prepared, as one half served as a control, while the other one was treated with fluoride gel. The specimens were examined with electron microscope at different magnifications. The findings show that fluoride gel applications affect the processes of mineralization and remineralization. This gives us the ground for applying fluoride gel in the clinical practice for prevention and treatment of caries incipiens.