Goals and methods of clinical studies
Kunz, R.; Zink, A.
Zeitschrift für Rheumatologie 59(1): 41-44
2000
ISSN/ISBN: 0340-1855 PMID: 10769423 Document Number: 523766
The validity of clinical patient-oriented research is always threatened by the influence of bias, confounding factors or random effects that might distort the results. However, the susceptibility to distortion varies between different study designs. The best protection against spurious relationships or distorted results are specific focused research questions and rigorous integration of sound study methodology during the design and performance phase.
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