Periodontal regeneration by application of the porous beta-TCP/BMP artificial bone to Class Ii furcation defects
Jia, X.; Fan, M.; Ren, T.
Zhonghua Kou Qiang Yi Xue Za Zhi 35(3): 200-202
2000
ISSN/ISBN: 1002-0098 PMID: 11780224 Document Number: 523263
To study the regeneration of periodontal tissue after the application of beta-TCP/BMP artificial bone to class II furcation defects. Periodontal defects were produced surgically around premolar teeth in 4 dogs. The flap surgery was performed and the root surfaces were curetted to remove the periodontal ligament and the cementum. A synthetic bioabsorble barrier manufactured from poly DL-lactide was used. The defects were divided into 3 groups (beta-TCP/BMP + PDLLA, PDLLA, control). 12 weeks after surgery, the animals were sacrificed and the teeth with their supporting periodontium were processed for light microscopic evaluation. The definitive evidences of regeneration were founded both in BMP/GTR group and GTR group, but the BMP/GTR group exhibited more new bone formation, cementum deposition occupying the majority of the furcation defects than the other two groups. It was concluded that the beta-TCP/BMP artificial bone can be used in GTR technique to promote periodontal regeneration.