Multiple ovarian biopsy in the treatment of women with polycystic ovary syndrome (PCOS)
Cibula, D.; Kuzel, D.; Rezabek, K.; Vrbikova, J.; Zivny, J.; Starka, P.L.
Clinical and Experimental Obstetrics and Gynecology 27(3-4): 194-196
2000
ISSN/ISBN: 0390-6663 PMID: 11214949 Document Number: 522499
Ovarian electrocautery has been used with success in the treatment of PCOS women. However, unipolar coagulation carries the risk of serious injuries to pelvic organs. In an effort to avoid this potential risk, the efficacy of multiple ovarian biopsy was evaluated in our study. Eleven PCOS patients were enrolled to the study. Four to eight biopsies were taken from both ovaries. The levels of LH, FSH, androgens and the reactivity of ACTH test were evaluated at standard intervals. The occurrence of ovulation was determined by ultrasound. Laparoscopy was followed by non-significant changes of endocrine parameters only. The ovulatory cycle was restored in only three women of the whole group. Our study did not prove the efficacy of multiple ovarian biopsy in the treatment of PCOS women. The procedure caused only minor changes in endocrine parameters and rarely restored ovulation.