Ifosfamide- and paclitaxel-based treatment of relapsed and refractory lymphoma
King, K.; Younes, A.
Seminars in Oncology 27(1 Suppl 1: 14-22
2000
ISSN/ISBN: 0093-7754 PMID: 10697039 Document Number: 522441
Several trials of new salvage therapies for relapsed and refractory non-Hodgkin's lymphoma are based on ifosfamide and paclitaxel. These programs variably Induce clinical remissions and prepare patients for stem cell and bone marrow transplantations. Ifosfamide-containing regimens are also being evaluated in the treatment of newly diagnosed patients. However, no data exist with regard to paclitaxel-containing regimens outside salvage settings. This report reviews the effects of these compounds in the treatment of relapsed and refractory non-Hodgkin's lymphoma and proposes likely directions for future study.