Assessment of urinary excretion of antimalarial drugs in large-scale chemotherapeutic eradication projects
Bruce-Chwatt, L.J.
Bulletin of the World Health Organization 20: 973-985
1959
ISSN/ISBN: 0042-9686 PMID: 13805135 Document Number: 522077
Assessment of the urinary excretion of an antimalarial drug is a useful means of checking the amount of drug administered and the regularity of intake. The author describes the various methods available for the qualitative and quantitative estimation of antimalarial drugs in urine and discusses their relative merits, with special reference to their suitability for use in the field. He points out the difficulties involved in estimating the urinary excretion of antimalarials in large-scale chemotherapeutic eradication projects and stress the importance of simplifying testing techniques as far as possible.