Determination of fenfluramine in corpse using GC/NPD and GC/MS

Sun, Y.

Fa Yi Xue Za Zhi 16(1): 21-23; 64

2000


ISSN/ISBN: 1004-5619
PMID: 12536428
Document Number: 520325
A method was described for the determination of fenfluramine by GC/MS in blood, urine, liver, lung, kidney and heart tissues. After liquid-liquid extraction of fenfluramine in the specimens obtained from autopsy, the samples were qualitatively identified by GC/MS, and quantitatively determined by GC/NPD. 4-phenyl butylamine was used as internal standard. The concentrations of fenfluramine in blood, urine and liver were 7.8 micrograms/ml, 64.2 micrograms/ml and 31.3 micrograms/g respectively. The findings of autopsy and the results of toxicological analysis were also discussed.

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