Diagnosis and surgical treatment of posterior fossa solid hemangioblastomas
Zhou, L.; Du, G.
Chinese Medical Journal 113(2): 129-132
2000
ISSN/ISBN: 0366-6999 PMID: 11775535 Document Number: 519898
To elucidate the diagnosis and surgical treatment of the posterior fossa solid hemangioblastomas (PFSHs). The data from 22 patients with PFSHs verified by surgery and pathology were analyzed retrospectively and a review of relevant literature was conducted. The preoperative definitive diagnosis rate was 13/22. Total tumor removal was achieved in 20 patients. Two of the 22 patients died after surgery, one of brain-stem injury and the other from an intracranial hemorrhage. Twenty patients were followed up for 2 months to 8 years (average, 2 years). Kamofsky scale was > or = 80 in 15 patients, 60-70 in 1 patient and not measured in 4 patients who died during follow-up. The causes of death were pneumonia (2 patients) and purulent meningitis (2). MRI and DSA (digital subtraction angiography) are major preoperative diagnostic modalities for PFSH, but PFSH remains a challenging benign neoplasm. Special microsurgical techniques and improved operative manipulation can improve surgical efficacy.