Angiotensin-converting enzyme inhibitors in the treatment of arterial hypertension
Babadzhan, V.D.
Likars'ka Sprava 2: 19-26
2000
ISSN/ISBN: 1019-5297 PMID: 10862468 Document Number: 519312
Angiotensin-converting enzyme (ACE) inhibitors have come into widespread use as a treatment option for patients with arterial hypertension, which fact can be explained by their apparent hypotensive effect, a small percent of side effects, protective effects on target organs, and a possibility of reversibility of essential hypertension- and symptomatic hypertensions-related changes in the cardiovascular system. There are a great many of drug preparations belonging in the group of ACE-inhibitors (capoten, enalapril, renitec (enalapril maleate), benazepril, quinapril, cilazopril, lizinopril, ramipril--to name but few of them. Specificities of different representatives of ACE-inhibitors, as to their clinical efficacy were found to be related to different pharmacokinetic properties of drugs.