Gastroesophageal reflux and respiratory diseases
Futsuhara, K.; Kanazawa, M.
Nihon rinsho. Japanese journal of clinical medicine 58(9): 1911-1916
2000
ISSN/ISBN: 0047-1852 PMID: 11004826 Document Number: 518185
There is a relationship between gastroesophageal reflux and respiratory diseases. Reflux may trigger and aggravate respiratory diseases especially bronchial asthma. Both clinical and experimental observations suggest that the pathogenic mechanisms may be a vagal reflex and/or microaspiration of gastric acid into the trachea. General measures to avoid reflux and proton pomp inhibitor together with inhaled corticosteroid are the choice for treatment of asthma associated with gastroesophageal reflux. Xanthine derivatives and beta 2 adrenergic agonist might be withheld in these patients. A laparoscopic surgical treatment may be an option for patients with persistent symptoms.