Disorders of bone metabolism in gastrointestinal and hepatic diseases
Van Daele, P.L.; Pols, H.A.
Nederlands Tijdschrift Voor Geneeskunde 144(10): 462-467
2000
ISSN/ISBN: 0028-2162 PMID: 10726154 Document Number: 516746
Gastrointestinal and hepatic diseases are frequently associated with metabolic bone disorders, especially osteoporosis and osteomalacia. Malabsorption of vitamin D and calcium are important aetiological factors, although other factors may contribute, like the use of glucocorticosteroids in the treatment of inflammatory bowel disease. Treatment is first of all focused on correction of calcium and vitamin D deficiency. In severe osteoporosis additional treatment with bisfosfonates needs serious consideration.