Mongolism, delayed fertilization and sexual behaviour
James, W.H.
Nature 219(5151): 279-280
1968
ISSN/ISBN: 0028-0836 PMID: 4233592 DOI: 10.1038/219279a0Document Number: 516604
GERMAN1 has suggested that some hours after ovulation the human ovum may deteriorate while still remaining fertilizable. If it is fertilized in this condition, he suggests, it may give rise to a mongol infant. The maternal age effect in mongolism, on this hypothesis, is caused by the decline in coital frequency with maternal age, the decline in coital frequency occasioning a greater risk of fertilizing a deteriorated ovum.
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