Plasmacytoma of the breast. A report of two cases diagnosed by aspiration biopsy
Cangiarella, J.; Waisman, J.; Cohen, J.M.; Chhieng, D.; Symmans, W.F.; Goldenberg, A.
Acta Cytologica 44(1): 91-94
2000
ISSN/ISBN: 0001-5547 PMID: 10667168 Document Number: 516056
BACKGROUND: Extramedullary plasmacytoma of the breast is an uncommon neoplasm, occurring either as a solitary tumor or as evidence of disseminated multiple myeloma. CASE: Two cases of plasmacytoma of the breast were diagnosed by fine needle aspiration cytology. Aspiration smears showed a dispersed population of plasmacytoid cells with eccentric nuclei, abundant cytoplasm and the characteristic paranuclear hof. CONCLUSION: The clinical, cytologic and immunophenotypic features of plasmacytoma are characteristic, and the importance of distinguishing these neoplasms from primary mammary tumors is important to avoid unnecessary surgery.