Vasoactive effects of femostone in women with metabolic postmenopausal syndrome
Malichenko, S.B.; Amial'eva, E.P.; Lazebnik, L.B.
Klinicheskaia Meditsina 78(6): 48-53
2000
ISSN/ISBN: 0023-2149 PMID: 10900872 Document Number: 515510
The metabolic postmenopausal syndrome (MPS) is characterized by a complex of metabolic disorders: lipid (76%), purin (56%), calcium-phosphorus (61%). There is also a rise in amplitude of spontaneous platelet aggregation (61%) and fibrinogen levels (78%). Clinically, these phenomena manifest in arterial hypertension and defective cerebral circulation. An estrogen-histogen drug femoston was tried for clinical effectiveness and tolerance in 40 females with MPS. Femoston was used in long-term regimen for 12 months. The response was observed in all the patients, all the above parameters underwent positive changes. The drug was well tolerated, side effects were moderate. No withdrawals occurred.